A 2×6 rafter can span 14 feet 8 inches when spaced 16 inches apart with No. 1-grade southern pine lumber on a roof with a 3/12 slope or less with a maximum live load of 20 pounds per square foot and a dead load of 15 psf. This may sound a little mplicated, so let’s break down what impacts the span when it mes to roof rafters.